Work Schedule
Standard (Mon-Fri)Environmental Conditions
Able to lift 40 lbs. without assistance, Cold Room/Freezers -22degreesF/-6degrees C, Laboratory Setting, Office, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.), Will work with hazardous/toxic materialsJob Description
Do you have a passion for innovative ideas and groundbreaking discoveries? With over $1 billion invested annually in R&D, at Thermo Fisher Scientific you’ll help solve some of the world’s toughest challenges, from giving cancer patients hope, ensuring safe drinking water and helping law enforcement tackle cases through forensics. We empower our teams to put science into meaningful action and give our R&D colleagues the autonomy, resources and tools they need to take science a step beyond.
Location/Division Specific Information
Lengnau Switzerland / Drug Substance Division (Biologics)
How will you make an impact?
Responsible for developing or transferring upstream development processes to support cGMP biopharmaceutical processes in manufacturing. You will work within an interdisciplinary team of scientists where you will learn and supply your skills and ideas to projects.
What will you do?
- Perform laboratory experiments to support the production of recombinant proteins (including mAbs). Perform media optimization, seed train development, bioreactor process development, and cell culture clarification.
- Interpret client documents and literature to strategize approaches for successful development activities.
- Responsible for performing in-depth analysis of analytical data and collaborate with the analytical team for method lifecycle review.
- Communicate findings and discuss relevance of your data to a multi-discipline team consisting of downstream process development scientists, analytical and formulation scientists, quality assurance, process engineers and our customers.
- Author, review and approve reports, study plans, protocols, SOPs, and work instructions. Document execution and results according to good documentation practices. Willingness to work weekends on a rotational basis. Infrequently, international travel (
- 10%) and participation at international calls throughout various time zones may be requested.
Who we are looking for: experience, skills & abilities
- Experience handling and maintaining mammalian cell culture with a proven understanding of cell and molecular biology.
- Technical experience with the following processes: bench scale bioreactors, pilot scale bioreactors, high throughout AMBR bioreactors, perfusion processes and Design of Experiments.
- Understand ICH guidelines to prepare for process characterization and process validation and qualification activities.
- Ability to work independently with excellent communication and prioritization skills.
How will you get here?
Education
- B.S. in Chem Eng, Biochemistry, Biology or related field with 8 yrs, Masters with 6 yrs, or Ph.D. with 5 yrs
Knowledge, Skills, Abilities
- Passion for learning the analytical methods required for successful process development!
- High attention to detail.
- Strong desire to learning new skills.
Work Schedule
- This is a full time Monday – Friday, alternating weekend coverage, estimated 41 hours a week.
