Internship - Engineered vascular models for safety (12 months)

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Institute of Human Biology (IHB) at Roche in Basel, Switzerland is hosting an internship position for a researcher to study engineered vasculature models on chips for safety applications. Our team aims to develop next-generation realistic human organ models, accurately recreating in vivo tissue complexity, intricate spatial organization of organ-specific cell types and integration with advanced microfluidic organ-on-chip systems for homeostasis, organ-function modeling, and long-term culture.

You will be part of a collaborative effort between the Institute of Human Biology (IHB) and the Pathology and Applied Safety Science (PASS) chapter in Pharmaceutical Sciences, which support drug development in pRED. As an internship student, you will be focusing on exploring experimental vascularized tissue models for drug safety questions. Combining cutting-edge 3D engineered systems and advanced imaging techniques, you will investigate the translatability of vascular tissue models to human clinical findings. This internship offers a unique opportunity to contribute to our mission of advancing pre-clinical predictivity and our commitment to the 3Rs.

You are currently enrolled in a university M.Sc. program in relevant subjects such as molecular biology, biotechnology, bioengineering, chemical biology, or related fields, or you have completed your degree in the respective subjects within the past 12 months.

• You have experience in primary cell culture. Prior experience with the culture of complex human model systems such as organoids is highly desirable.

• Prior experience with engineered endothelial models, microscopy imaging and microfluidic organs on chips is highly desirable.

• You are fluent in English and highly curious about science and are able to derive novel approaches and ideas from published literature.

• You want to work in a highly collaborative environment where scientific exchange is highly valued.

• You are able to plan and perform experiments independently including their thorough interpretation and efficient documentation.

Your impact

• Interpret experimental data and report these in presentations and a written report to colleagues

Your application

Your complete application should include the following documents:

• An up-to-date CV and a Motivation Letter

• A certificate of enrollment (if you are currently studying)

• For Non-EU/EFTA citizens: Due to regulations, you must provide a letter from your university stating that an internship is mandatory for your studies and specifying the required length of the internship. Please upload this letter, along with your enrollment certificate, CV, and motivation letter.

Employment: 100%

Start date: As soon as possible

Duration: 12 months

Location: Basel, Switzerland

This internship is not suitable for thesis writing.

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.